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Could Ultraviolet B Irradiance and Vitamin D be Associated with Lower Incidence Rates of Lung Cancer?

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http://jech.bmj.com/content/62/1/69.abstract

http://www.polymvasurvivors.com/index.html

 

* High vitamin D levels (based on latitude and UV exposure) also correlate with a decreased risk of developing lung cancer, a 45% and 65% reduction in men and women respectively. Similar effects have been demonstrated in colonprostaterenal and endometrial cancer

 

 

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Could Ultraviolet B Irradiance and Vitamin D be Associated with Lower Incidence Rates of Lung Cancer?

 

 

Abstract

 

Background: 

This study examines whether insufficient ultraviolet B (UVB) irradiance, a marker of vitamin D inadequacy, might contribute to lung cancer incidence.

 

 

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Methods: 

The association of latitude and UVB irradiance with age-adjusted incidence rates of lung cancer in 111 countries was investigated. Independent associations with UVB irradiance, cloud cover, anthropogenic aerosols, and cigarette smoking, were assessed using multiple regression.

 

 

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Results: 

Latitude was positively related to incidence rates in men (R2  =  0.55, p<0.01) and women (R2  =  0.36, p<0.01). In men, cigarette consumption (p<0.001) was positively related to risk, whereas UVB irradiance was inversely associated (p = 0.003).

 

There were positive associations with UVB absorbers, in particular cloud cover (p = 0.05) and aerosol optical depth (p = 0.005). The R2 for the model was 0.78 (p<0.001).

 

UVB irradiance was also inversely associated with incidence rates in women (p = 0.0002), whereas cigarette consumption (p<0.001), total cloud cover (p = 0.02) and aerosol optical depth (p = 0.005) were positively associated. The R2 for the model was 0.77 (p<0.001).

 

 

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Conclusions: 

Lower levels of UVB irradiance were independently associated with higher incidence rates of lung cancer in 111 countries.

 

 

 

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http://jech.bmj.com/content/62/1/69.abstract

http://www.polymvasurvivors.com/index.html

 

   

 

 

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